Title:
デシタビンポリモルフの組成物及び処方物並びにその使用方法
Document Type and Number:
Japanese Patent JP5159307
Kind Code:
B2
Abstract:
Pharmaceutical compositions and methods for treatment of neoplastic conditions using polymorphs of decitabine are provided. Also provided are methods for manufacturing and administering such pharmaceutical compositions.
Inventors:
Red Car Sanjeev
Joshi Hangar Rajashuri
Joshi Hangar Rajashuri
Application Number:
JP2007521565A
Publication Date:
March 06, 2013
Filing Date:
July 12, 2005
Export Citation:
Assignee:
Astex Pharmaceuticals, Inc.
International Classes:
C07H19/12; A61K31/706; A61P7/00; A61P7/06; A61P9/10; A61P9/14; A61P35/00; A61P35/02; A61P43/00; B01D9/02
Domestic Patent References:
| JP55027077A | ||||
| JP49016435A |
Foreign References:
| US3350388 |
Other References:
BEN-HATTAR,J. et al,An improved synthesis of 2'-deoxy-5-azacytidine by condensation of an 9-fluorenylmethoxycarbonyl-protected sugar onto the silylated base,Journal of Organic Chemistry,1986年,Vol.51, No.16,pp.3211-3213
WINKLEY,M.W. et al,Direct glycosylation of 1,3,5-triazinones. New approach to the synthesis of the nucleoside antibiotic 5-azacytidine (4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2-one) and related derivatives,Journal of Organic Chemistry,1970年,Vol.35, No.2,pp.491-495
DAVIES,M.J. et al,Structure of 2'-deoxy-5-azacytidine (decitabine) monohydrate,Acta Crystallographica, Section C: Crystal Structure Communications,1991年,Vol.C47, No.7,pp.1418-1420
化学実験操作法 上巻,1963年,pp.371-399
WINKLEY,M.W. et al,Direct glycosylation of 1,3,5-triazinones. New approach to the synthesis of the nucleoside antibiotic 5-azacytidine (4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2-one) and related derivatives,Journal of Organic Chemistry,1970年,Vol.35, No.2,pp.491-495
DAVIES,M.J. et al,Structure of 2'-deoxy-5-azacytidine (decitabine) monohydrate,Acta Crystallographica, Section C: Crystal Structure Communications,1991年,Vol.C47, No.7,pp.1418-1420
化学実験操作法 上巻,1963年,pp.371-399
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama