Title:
抗ヒトテネイシンモノクローナル抗体
Document Type and Number:
Japanese Patent JP5191036
Kind Code:
B2
Abstract:
An anti-human tenascin monoclonal antibody is described, whose light and heavy chain variable region sequences are SEQ ID 1 and SEQ ID 2, respectively, its proteolytic fragments capable of binding to an antigenic epitope within the region A(1-4)-D of human tenascin, its recombinant derivatives, its conjugates and its similar functional analogues capable of binding to an antigenic epitope within the A(1-4)-D region of human tenascin.
Inventors:
Rita de Santis
Angela Pelliccia
Giovanna Palombo
Paolo Carminati
Angela Pelliccia
Giovanna Palombo
Paolo Carminati
Application Number:
JP2007500356A
Publication Date:
April 24, 2013
Filing Date:
February 16, 2005
Export Citation:
Assignee:
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SOCIETA PER AZIONI
International Classes:
C07K16/18; A61K39/395; A61K45/00; A61K51/00; A61P35/00; C07K16/30; C07K16/46; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; G01N33/574; G01N33/577; C12P21/08
Domestic Patent References:
| JP2002234900A | ||||
| JP2003512300A |
Foreign References:
| US6335014 | ||||
| WO2003072608A1 | ||||
| WO2002066075A1 | ||||
| WO2003075960A1 |
Other References:
FEBS LETTERS,1993年,Vol.332, No.1, 2,p.39-43
European Journal of Nuclear Medicine,1999年,Vol.26, No.4,p.348-357
European Journal of Nuclear Medicine,1999年,Vol.26, No.4,p.348-357
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Michiko Matsutani
Kenji Tomita
Mina Shiga
Hiroshi Yamazaki
Michiko Matsutani
Kenji Tomita
Mina Shiga