Title:
HER-3に対して誘導された抗体及びその使用
Document Type and Number:
Japanese Patent JP5207979
Kind Code:
B2
Abstract:
The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin.
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Inventors:
Rote, Mike
Trader, Martin
Hartman, Susan
Freeman, Dan
Radine ski, bob
Borges, Eritsk
Trader, Martin
Hartman, Susan
Freeman, Dan
Radine ski, bob
Borges, Eritsk
Application Number:
JP2008547904A
Publication Date:
June 12, 2013
Filing Date:
December 29, 2006
Export Citation:
Assignee:
U3 PHARMA
International Classes:
C07K16/30; A61K39/395; A61P35/00; A61P43/00; G01N33/574; C12N15/09; C12P21/08
Domestic Patent References:
| JP2005533488A | ||||
| JP2005504044A | ||||
| JP2001523973A |
Foreign References:
| US20040071696 | ||||
| US20020064805 |
Other References:
Br. J. Cancer,1994年,Vol.70, No.3,pp.459-465
Attorney, Agent or Firm:
Kuramochi Akiko
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura