Title:
キナーゼ阻害剤としての化合物および組成物
Document Type and Number:
Japanese Patent JP5214799
Kind Code:
B2
Abstract:
The invention relates to triazine and pyrimidine derivatives having Formula (1) or (2), and methods for using such compounds. For example, the compounds of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-IR), and/or insulin receptor (InsR) or a combination thereof.
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Inventors:
Tao Jiang
Pierre-Eve Michelle
Truk Ngok Nguyen
Pay way
U Baogen
Suefeng Chu
Pierre-Eve Michelle
Truk Ngok Nguyen
Pay way
U Baogen
Suefeng Chu
Application Number:
JP2011504085A
Publication Date:
June 19, 2013
Filing Date:
April 03, 2009
Export Citation:
Assignee:
IRM,LLC
International Classes:
C07D487/04; A61K31/519; A61K31/53; A61K31/5365; A61P31/00; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P43/00
Domestic Patent References:
JP2006160628A | ||||
JP2006523219A | ||||
JP2006502184A | ||||
JP2007523953A | ||||
JP2006519226A |
Foreign References:
US20080070893 | ||||
WO2006068954A2 | ||||
WO2004087707A1 | ||||
WO2005035516A1 |
Other References:
Bioorganic Medicinal Chemistry Letters,2007年,17,pp.4191-4195
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai