Title:
新規環状ペプチド化合物
Document Type and Number:
Japanese Patent JP5218051
Kind Code:
B2
Abstract:
The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
Inventors:
Masahiro Kaoru
Seiji Yoshimura
Ikki Kamijo
Makino Takuya
Yasuda Minoru
Toshio Yamanaka
Eisaku Tsujii
Sachiko Yamagishi
Seiji Yoshimura
Ikki Kamijo
Makino Takuya
Yasuda Minoru
Toshio Yamanaka
Eisaku Tsujii
Sachiko Yamagishi
Application Number:
JP2008521463A
Publication Date:
June 26, 2013
Filing Date:
October 26, 2006
Export Citation:
Assignee:
Astellas Pharma Inc.
International Classes:
C07K7/64; A61K38/00; A61P31/14
Domestic Patent References:
| JP2004517818A | ||||
| JP5271267A |
Foreign References:
| WO2005032576A1 | ||||
| WO2005021028A1 |
Other References:
Helvetica Chimica Acta,1997年,Vol.80,p.695-705
Attorney, Agent or Firm:
Morita Taku
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke