Title:
KCNQ2/3K+チャンネルに対する親和性を有する置換されたテトラヒドロピロロピラジン化合物及びその医薬中での使用
Document Type and Number:
Japanese Patent JP5256203
Kind Code:
B2
Abstract:
Substituted tetrahydropyrrolopyrazine compounds corresponding to the formula I: processes for their preparation, pharmaceutical compositions comprising these compounds and the use of these compounds for the treatment and/or inhibition of pain and other disorders or disease states at least partly mediated by KCNQ2/3 K+ channels.
Inventors:
Merla Beatrix
Christoph Thomas
Oberberch Stefan
Sine Claus
Barenberg Berg Gregor
Frank robert
Kunert sven
Schroeder Wolfgang
Christoph Thomas
Oberberch Stefan
Sine Claus
Barenberg Berg Gregor
Frank robert
Kunert sven
Schroeder Wolfgang
Application Number:
JP2009532715A
Publication Date:
August 07, 2013
Filing Date:
October 16, 2007
Export Citation:
Assignee:
Grunenthal Gesellschaft Mito Beschlenktel Haftung
International Classes:
C07D487/04; A61K31/4985; A61P13/02; A61P25/04; A61P25/06; A61P25/08; A61P25/22; A61P25/28
Domestic Patent References:
JP2006514942A | ||||
JP6239865A | ||||
JP6041132A | ||||
JP2005523395A |
Foreign References:
US4188389 | ||||
WO2006048750A1 |
Attorney, Agent or Firm:
Mitsufumi Esaki
Blacksmith
Blacksmith