Title:
置換キサンチン誘導体
Document Type and Number:
Japanese Patent JP5292413
Kind Code:
B2
Abstract:
A pharmaceutical composition comprising:
a. an effective amount of a compound of Formula B:
or a pharmaceutically acceptable salt thereof;
b. a second therapeutic agent selected from insulin or insulin analogues, glucagon-like-peptide-1 (GLP-1) receptor agonists, sulfonylurea agents, biguanide agents, alpha-glucosidase inhibitors, PPAR agonists, meglitinide agents, dipeptidyl-peptidase (DPP) IV inhibitors, phosphodiesterase inhibitors, amylin agonists, CoEnzyme A inhibitors, and antiobesity agents; and
c. a pharmaceutically acceptable car.
Inventors:
Toon Roger Dee.
Ryu Julie F.
Herbson Scott El.
Ryu Julie F.
Herbson Scott El.
Application Number:
JP2010548745A
Publication Date:
September 18, 2013
Filing Date:
February 27, 2009
Export Citation:
Assignee:
Concert Pharmaceuticals Incorporated
International Classes:
C07D473/10; A61K31/522; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P7/02; A61P9/10; A61P9/12; A61P13/02; A61P13/12; A61P19/06; A61P27/02
Domestic Patent References:
JP9510717A | ||||
JP2009511481A |
Other References:
KUSHNER DJ,PHARMACOLOGICAL USES AND PERSPECTIVES OF HEAVY WATER AND DEUTERATED COMPOUNDS,CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY,カナダ,1999年 2月 1日,V77 N2,P79-88
FOSTER A B,DEUTERIUM ISOTOPE EFFECTS IN THE METABOLISM OF DRUGS AND XENOBIOTICS: IMPLICATIONS FOR DRUG DESIGN,ADVANCED IN DRUG RESEARCH,英国,ACADEMIC PRESS,1985年 1月 1日,V14,P1-40
Journal of Pharmacology and Experimental Therapeutics,1997年,Vol.284, No.1,pp.337-345
Chirality,2002年,Vol.14, No.8,pp.643-652
FOSTER A B,DEUTERIUM ISOTOPE EFFECTS IN THE METABOLISM OF DRUGS AND XENOBIOTICS: IMPLICATIONS FOR DRUG DESIGN,ADVANCED IN DRUG RESEARCH,英国,ACADEMIC PRESS,1985年 1月 1日,V14,P1-40
Journal of Pharmacology and Experimental Therapeutics,1997年,Vol.284, No.1,pp.337-345
Chirality,2002年,Vol.14, No.8,pp.643-652
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto