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Title:
フーリエ変換赤外振動円二色性分光法を使用したキラル分子の反応モニタリング
Document Type and Number:
Japanese Patent JP5313450
Kind Code:
B2
Abstract:
A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a VCD spectra and an IR spectra of the chemical compounds in the reaction, and manipulating the spectra to obtain a % EE value. Using such real time information, the reaction parameters can be changed to shift the reaction to produce more of one chiral molecule than another.

Inventors:
Nafi, Lawrence, A.
Kuo, Changnin.
Ducor, Rina, Kay.
Application Number:
JP2006535412A
Publication Date:
October 09, 2013
Filing Date:
October 13, 2004
Export Citation:
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Assignee:
BIO TOOLS,INC.
International Classes:
G01N21/19; G01N21/35; G01N21/75; G01N21/05
Domestic Patent References:
JP2005069998A
JP2000206036A
Other References:
D. Tsankov, T. Eggimann, and H. Wieser ,Alternative Design for Improved FT-IR/VCD Capabilities,Applied Spectroscopy,1995年,Vol. 49, No. 1,pp. 132-138
Attorney, Agent or Firm:
Tadao Hirata