Title:
MDM2とp53の間の相互作用の阻害剤
Document Type and Number:
Japanese Patent JP5385125
Kind Code:
B2
Abstract:
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, s, t, R1, R2, A and Z have defined meanings.
Inventors:
Lachlan, Jean Jan Fernand Armand
Mayet, Christoph
Brno
Raldeyou, Delphine Yvonne Raymond
Poncelet, Alan Filip
Van Feift, Liyuk
Mayet, Christoph
Brno
Raldeyou, Delphine Yvonne Raymond
Poncelet, Alan Filip
Van Feift, Liyuk
Application Number:
JP2009500841A
Publication Date:
January 08, 2014
Filing Date:
March 19, 2007
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D401/12; A61K31/443; A61K31/4439; A61K31/444; A61P1/04; A61P1/18; A61P3/00; A61P3/06; A61P3/10; A61P5/14; A61P11/00; A61P13/02; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P15/08; A61P15/14; A61P17/00; A61P19/00; A61P21/00; A61P21/04; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P31/00; A61P31/20; A61P35/00; A61P35/02; A61P37/02; A61P43/00; C07D405/12; C07D471/04; C07D495/04
Domestic Patent References:
| JP2004532209A | ||||
| JP2059577A | ||||
| JP2008513532A |
Foreign References:
| WO2005061519A1 | ||||
| WO2005108397A1 | ||||
| US20040077853 | ||||
| US2419199 | ||||
| WO2005066139A1 | ||||
| WO2006124692A1 | ||||
| WO2003040402A1 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office