Title:
多次元プローブ分析法によるC型肝炎ウイルス型判定のためのプローブ及び方法
Document Type and Number:
Japanese Patent JP5405715
Kind Code:
B2
Abstract:
The present invention relates to methods for modifying the emission of light from labeled nucleic acids for the purpose of real time detection, analysis, and quantitation of nucleic acid sequences, e.g., using singly labeled probes. These methods and reagents exploit advantageous properties of thiazine dyes and diazine dyes. Furthermore, the use of these soluable light emission modifiers in background reduction, nucleic acid duplex stabilization and other uses is also described. Related kits, reaction mixtures and integrated systems are described.
Inventors:
Amar Gupta
Stephen Gordon Will
Stephen Gordon Will
Application Number:
JP2006180022A
Publication Date:
February 05, 2014
Filing Date:
June 29, 2006
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C12N15/09; C12Q1/68; C12Q1/70; G01N21/78; G01N33/53; G01N33/569; G01N33/576; G06F19/00
Other References:
Journal of Clinical Microbiology、2002年、Vol.40、No.6、pp.2046-2020
Clinical Chemistry、2002年、Vol.48、No.12、pp.2147-2154
Molecular Genetics and Metabolism、2004年、Vol.81、pp.237-243
Clinical Chemistry、2002年、Vol.48、No.12、pp.2147-2154
Molecular Genetics and Metabolism、2004年、Vol.81、pp.237-243
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima