Title:
PCV-DNAワクチン
Document Type and Number:
Japanese Patent JP5410472
Kind Code:
B2
Abstract:
The invention relates to immunogenic preparations or vaccines comprising, on the one hand, a plasmid encoding and expressing a gene from PCV, in particular selected from the group consisting of ORF1 of PCV-2, ORF2 of PCV-2, ORF1 of PCV-1 and ORF2 of PCV-1, and, on the other hand, an element capable of increasing the immune response directed against the product of expression of the gene, which can be a carbomer, a porcine cytokine, e.g. GM-CSF or a cationic lipid of formula in which R1 is a saturated or unsaturated linear aliphatic radical having from 12 to 18 carbon atoms, R2 is another aliphatic radical comprising from 2 to 3 carbon atoms, andt X is an hydroxyle ou amine group. The cationic lipid can be DMRIE, possibly coupled with DOPE.
Inventors:
O'Donne, Jean-Christophe, Francis
Bublo, michel
Pere, jennifer, maria
Charelle, Catherine, Elizabeth
Bublo, michel
Pere, jennifer, maria
Charelle, Catherine, Elizabeth
Application Number:
JP2011116460A
Publication Date:
February 05, 2014
Filing Date:
May 25, 2011
Export Citation:
Assignee:
Merial SS
International Classes:
A01N63/00; A61K39/12; A01N65/00; C12N15/09; A61K9/00; A61K9/127; A61K31/711; A61K39/39; A61K47/18; A61K48/00; A61P31/12; C07K14/01; C07K14/535; C12N15/74
Foreign References:
| WO1999018214A1 |
Other References:
Vaccine,1997年,vol.15, no.8,p.818-820
Attorney, Agent or Firm:
Takashi Koshiba