Title:
オメプラゾール含有医薬製剤
Document Type and Number:
Japanese Patent JP5412021
Kind Code:
B2
Abstract:
An enteric coated oral pharmaceutical formulation comprising as active ingredient a compound selected from the group of omeprazole, an alkaline salt of omeprazole, one of the single enantiomers of omeprazole and an alkaline salt of one of the single enantiomers of omeprazole, wherein the formulation comprises a core material that comprises the active ingredient and optionally an alkaline reacting compound, the active ingredient is in admixture with a pharmaceutically acceptable excipient, such as for instance a binding agent, and on said core material a separating layer and an enteric coating layer. A hydroxypropyl cellulose (HPC) with a specific cloud point is used in the manufacture of the claimed pharmaceutical formulations. Furthermore, the application describes the processes for their preparation and the use of the claimed formulations in medicine.
Inventors:
Pontus Bell Estrand
Peter Wang
Peter Wang
Application Number:
JP2000580597A
Publication Date:
February 12, 2014
Filing Date:
November 03, 1999
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
A61K31/454; A61K9/20; C07D401/12; A61K9/22; A61K9/36; A61K9/50; A61K31/4427; A61K31/4439; A61K47/32; A61K47/38; A61P1/00
Domestic Patent References:
| JP11501950A |
Attorney, Agent or Firm:
Junji Yuda