Title:
ステアロイル-CoAデサチュラーゼのヘテロ環式阻害剤
Document Type and Number:
Japanese Patent JP5507474
Kind Code:
B2
Abstract:
The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed.
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Inventors:
Sultan Chowdhury
Natalie Dales
Julia Fonarev
Jiang Min Hu
Duangie hou
Ki Jia
Vishnu Mercy Kodomur
Natalia Pokrovskya
Xiao Soon
Zaifui Chan
Natalie Dales
Julia Fonarev
Jiang Min Hu
Duangie hou
Ki Jia
Vishnu Mercy Kodomur
Natalia Pokrovskya
Xiao Soon
Zaifui Chan
Application Number:
JP2010547169A
Publication Date:
May 28, 2014
Filing Date:
February 18, 2009
Export Citation:
Assignee:
Novartis Age
International Classes:
C07D417/04; A61K31/427; A61K31/437; A61K31/4439; A61K31/497; A61K31/501; A61K31/506; A61K45/00; A61P3/00; A61P3/04; A61P3/10; A61P5/50; A61P7/02; A61P9/12; A61P17/00; A61P17/02; A61P17/06; A61P17/10; A61P19/06; A61P43/00; C07D417/14; C07D471/04
Domestic Patent References:
| JP49070968A | ||||
| JP4972690B2 |
Foreign References:
| WO2008024390A1 | ||||
| WO2006034440A1 | ||||
| WO2007130075A1 | ||||
| WO2008036715A1 | ||||
| WO2008074835A1 | ||||
| WO2009101917A1 | ||||
| WO2006010642A1 |
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki