Title:
分子
Document Type and Number:
Japanese Patent JP5536427
Kind Code:
B2
Abstract:
We describe an rspd(n/CRD) polypeptide, fragment, homologue, variant or derivative thereof for use in a method of treatment or prophylaxis of a disease. A method of treating an individual suffering from a disease or preventing the occurrence of a disease in an individual is also described, in which the method comprises administering to the individual a therapeutically or prophylactically effective amount of an rspd (n/CRD) polypeptide, fragment, homologue, variant or derivative thereof. Preferably, the rspd (n/CRD) polypeptide and nucleic acid comprise SEQ ID NO: 1 and SEQ ID NO: 2, respectively.
Inventors:
Clark, Howard
Nadesalingham, Paranya
Reed, Kenneth Bannerman Milne
Strong, Peter
Nadesalingham, Paranya
Reed, Kenneth Bannerman Milne
Strong, Peter
Application Number:
JP2009272082A
Publication Date:
July 02, 2014
Filing Date:
November 30, 2009
Export Citation:
Assignee:
Medical Research Council
International Classes:
A61K38/00; G01N33/50; A61K35/76; A61K48/00; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P27/02; A61P27/04; A61P27/16; A61P29/00; A61P31/00; A61P31/04; A61P31/12; A61P35/00; A61P37/00; A61P37/08; A61P43/00; C07K14/47; C07K14/785; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12Q1/02; C12Q1/68; G01N33/15; G01N33/566
Foreign References:
| EP1108786A1 |
Other References:
Biochemical Journal,1996年,Vol.318,No.2,P.505-511
Biochemical Journal,1992年,Vol.284,No.3,P.795-802
Biochemical Journal,1997年,Vol.323,No.2,P.393-399
The Journal of Biological Chemistry,1993年,Vol.268,No.4,P.2976-2983
The Journal of Clinical Investigation,2001年 2月,Vol.107,No.4,P.467-475
American Journal of Respiratory and Critical Care Medicine,1998年,Vol.158,No.2,P.510-518
Biochemical Journal,1992年,Vol.284,No.3,P.795-802
Biochemical Journal,1997年,Vol.323,No.2,P.393-399
The Journal of Biological Chemistry,1993年,Vol.268,No.4,P.2976-2983
The Journal of Clinical Investigation,2001年 2月,Vol.107,No.4,P.467-475
American Journal of Respiratory and Critical Care Medicine,1998年,Vol.158,No.2,P.510-518
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo