Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
塩基性薬効成分の脂肪酸塩、安息香酸塩を含有する外用剤とその製造方法
Document Type and Number:
Japanese Patent JP5544544
Kind Code:
B2
Abstract:
It has been demanded to develop a formulation for a novel external preparation having excellent transdermal absorption of a basic pharmacologically active component contained therein. It is found that the lipid solubility (logP values) of a basic pharmacologically active component and an organic acid (particularly a fatty acid) contribute significantly to the transdermal absorption of the basic pharmacologically active component in the selection of proper combinations of the basic pharmacologically active component and the organic acid. Namely, it is found that superior transdermal absorption of a basic pharmacologically active component having a lipid solubility level of 0.5 to 5 can be achieved by forming a salt of the component with a fatty acid having a lipid solubility level of -1 to 4. Thus, it becomes possible to provide a novel external preparation having excellent transdermal absorption properties.

More Like This:
JP2023182599PEPTIDE YY PHARMACEUTICAL FORMULATION, COMPOSITION, AND METHOD
JP6736656Pharmaceutical prescription
JP2007501255Preservation of blood cells
Inventors:
Noritaka Hanma
Sakaki Ishibashi
Hidetoshi Hamamoto
Katsuhiro Yamanaka
Application Number:
JP2010523743A
Publication Date:
July 09, 2014
Filing Date:
August 03, 2009
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
Incorporated company MEDRx
International Classes:
A61K47/12; A61K9/70; A61K47/10; A61K47/14
Domestic Patent References:
JPH08225448A1996-09-03
JPH07215850A1995-08-15
JP2006169238A2006-06-29
JP2001517669A2001-10-09
JPH08225448A1996-09-03
JPH07215850A1995-08-15
JP2006169238A2006-06-29
JP2001517669A2001-10-09
Foreign References:
WO2001007018A12001-02-01
WO2001007018A12001-02-01
Attorney, Agent or Firm:
Mitsuo Tanaka
Yamada Takuji
Michiko Matsutani
Satoshi Hashimoto



 
Previous Patent: JPS5544543

Next Patent: MATERIAL FOR HIGH PRESSURE FUEL INJECTION PIPE AND MANUFACTURE THEREOF