Title:
レニン阻害剤としての３，４−置換ピペリジン誘導体
Document Type and Number:
Japanese Patent JP5587246
Kind Code:
B2
Abstract:
The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.
Inventors:
A chain, Austin, Chee * ユ
デューブ, Daniel
フォルニ yell and Pierre * Andre
Grimm, Erich, El.
Lacombe, Patrick
A lari belt, Sebastian
McDonald's, Dwight
McKay and Dee. blues
McKay, Daniel, James
Wu, Tom, and Yao * -- pretty
Campo, Louis * Charles
Scott, Jeremy, Peter
Blur me, ER, Nadine
デューブ, Daniel
フォルニ yell and Pierre * Andre
Grimm, Erich, El.
Lacombe, Patrick
A lari belt, Sebastian
McDonald's, Dwight
McKay and Dee. blues
McKay, Daniel, James
Wu, Tom, and Yao * -- pretty
Campo, Louis * Charles
Scott, Jeremy, Peter
Blur me, ER, Nadine
Application Number:
JP2011123054A
Publication Date:
September 10, 2014
Filing Date:
June 01, 2011
Export Citation:
Assignee:
アクテリオン Fame shoe tee カルズ Limited Actelion Pharmaceuticals Ltd
International Classes:
C07D401/04; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/506; A61K31/5377; A61P3/10; A61P5/42; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P15/10; A61P17/00; A61P25/22; A61P25/28; A61P27/02; A61P27/06; A61P37/02; A61P43/00; C07D401/14
Attorney, Agent or Firm:
Iwase Yoshiwa
Makoto Ono
Yoshinori Kanayama
Michiaki Tsubokura
Kazuteru Shigemori
Kenji Ando
Yasufumi Shiroyama
Makoto Ono
Yoshinori Kanayama
Michiaki Tsubokura
Kazuteru Shigemori
Kenji Ando
Yasufumi Shiroyama