Title:
生物由来の生理活性物質の測定方法及び測定用試薬キット
Document Type and Number:
Japanese Patent JP5629306
Kind Code:
B2
Abstract:
Discolosed is a technique which simplifies the adjustment of a reagent which makes the proteins contained in limulus amoebocyte lysate (LAL) attach to the surface of microparticles dispersed in a prepared drug solution, and which can improve the accuracy of the detection of a predetermined physiologically active substance or the measurement of the concentration thereof. A reagent is prepared which adsorbs the proteins contained in LAL to beads dispersed in a drug solution prepared in advance. By reacting a sample containing an endotoxin with the reagent, groups of the beads associate and rapidly form large aggregates, and measurement of the endotoxin is carried out by the detecting the formation of the aggregates. The beads are formed from an inorganic material such as alumina, kaolin, or manganese oxide.
Inventors:
薮崎 克己
Application Number:
JP2012501599A
Publication Date:
November 19, 2014
Filing Date:
February 26, 2010
Export Citation:
Assignee:
興和株式会社
International Classes:
G01N33/579
Domestic Patent References:
| JP2009150723A | 2009-07-09 | |||
| JPH0658938A | 1994-03-04 | |||
| JPS61181966A | 1986-08-14 |
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Takehiko Sekine
Toshiaki Shimoda
Takehiko Sekine
Toshiaki Shimoda