Title:
ポリ乳酸微粒子の製造方法、ポリ乳酸微粒子、並びにこれを用いた結晶核剤、成形体、及び表面改質剤
Document Type and Number:
Japanese Patent JP5652831
Kind Code:
B2
Abstract:
Provided is a method for producing polylactic acid microparticles, which comprises: a preliminary step in which a polymer compound solution, which is obtained by dissolving in a first solvent a polymer compound containing structural units derived from l-lactic acid and structural units derived from d-lactic acid, is retained in a first liquid retaining part while a second solvent, which is a poor solvent of the polymer compound, is retained in a second liquid retaining part of a permeation device having two liquid retaining parts separated by a permeation membrane having pores with a diameter of 0.5 nm to 1,000 nm; and a permeation step in which the polymer compound solution retained in the first liquid retaining part is brought into contact with the second solvent by causing the polymer compound solution to permeate through the permeation membrane at a flow rate of 1×10-3 mL/(min·cm2) to 10,000 mL/(min·cm2).
Inventors:
上原 宏樹
山延 健
山延 健
Application Number:
JP2012514770A
Publication Date:
January 14, 2015
Filing Date:
April 28, 2011
Export Citation:
Assignee:
国立大学法人群馬大学
International Classes:
C08J3/14; C08J7/04; C08L67/04
Domestic Patent References:
| JP2005290257A | 2005-10-20 | |||
| JP2010084075A | 2010-04-15 | |||
| JP2006348141A | 2006-12-28 | |||
| JP2003073533A | 2003-03-12 | |||
| JPH08193124A | 1996-07-30 | |||
| JP2007297465A | 2007-11-15 |
Foreign References:
| WO2006088241A1 | 2006-08-24 | |||
| WO2011024693A1 | 2011-03-03 |
Attorney, Agent or Firm:
Nakajima 淳
Kato Kazu -- full
Hiroshi Fukuda
Kato Kazu -- full
Hiroshi Fukuda