Title:
多量体マルチエピトープインフルエンザワクチン
Document Type and Number:
Japanese Patent JP5654345
Kind Code:
B2
Abstract:
An isolated polynucleotide encoding an influenza multi-epitope polypeptide, wherein the multi-epitope polypeptide comprises multiple copies of a plurality of influenza virus peptide epitopes wherein the polypeptide is B(X1ZX2Z . . . Xm)nB or B(X1)nZ(X2)nZ . . . (Xm)nB; wherein B is an optional sequence of 1-4 amino acid residues; n is at each occurrence independently an integer of 2-50; m is an integer of 3-15; each of X1, X2 . . . Xm is an influenza peptide epitope of 4-24 amino acid residues; and Z at each occurrence is a bond or a spacer of 1-4 amino acid residues.
Inventors:
ベン−イエディディア タマール
シンガー ヨッシー
シンガー ヨッシー
Application Number:
JP2010518815A
Publication Date:
January 14, 2015
Filing Date:
August 03, 2008
Export Citation:
Assignee:
ビオンドヴァックス ファーマシューティカルズ リミテッド
International Classes:
C12N15/09; A61K39/145; A61K39/39; C07K14/11
Attorney, Agent or Firm:
Kazuko Fujita