Title:
２−シリロキシ−ピロールを使用する３−（（ピロール−２−イル）メチレン）−２−ピロロンの調製方法
Document Type and Number:
Japanese Patent JP5732541
Kind Code:
B2
Abstract:
The present invention provides for synthetic processes for the making of substituted 3-((pyrrol-2-yl)methylene)-2-pyrrolones, including sunitinib. The present invention also provides for a process of crystallizing substantially pure sunitinib L-malate.
Inventors:
Henske, Julian Pee
Chen, Yun-fa
Chen, Yun-fa
Application Number:
JP2013535230A
Publication Date:
June 10, 2015
Filing Date:
November 01, 2010
Export Citation:
Assignee:
Sino Farm (Kunshan) Biochemical Technology Company Limited
International Classes:
C07D403/06
Foreign References:
| CN101497607A | ||||
| US20060009510 | ||||
| US20050059824 |
Attorney, Agent or Firm:
Kimura Mitsuru
Takanori Mamoru
Taiji Morikawa
Amamiya Yasuhito
Kei Sakurada
Mie Hideki
Takanori Mamoru
Taiji Morikawa
Amamiya Yasuhito
Kei Sakurada
Mie Hideki