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Title:
HCVプロテアーゼ阻害剤およびその使用
Document Type and Number:
Japanese Patent JP5755450
Kind Code:
B2
Abstract:
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Inventors:
New, Daechan
Petter, Russell
Shin, Jaswinder
Krug, Arthur F.
Chao, Lee Shin
Application Number:
JP2010539887A
Publication Date:
July 29, 2015
Filing Date:
December 19, 2008
Export Citation:
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Assignee:
Celgene Abilomics Research, Inc.
International Classes:
C07K5/078; A61K38/00; A61K45/00; A61P1/16; A61P31/14; C07K5/08
Domestic Patent References:
JP2006507264A
JP2006511193A
JP2011509242A
Foreign References:
WO2007015855A1
WO2007040049A1
WO2005113581A1
Other References:
DE FRANCESCO, R. et al.,"Advances in the development of new therapeutic agents targeting the NS3-4A serine protease or the NS5B RNA-dependent RNA polymerase of the hepatitis C virus.",ADVANCED DRUG DELIVERY REVIEWS,2007年10月10日,Vol.59, No.12,P.1242-1262
PERNI, R.B. et al.,"Inhibitors of hepatitis C virus NS3・4A protease. Part 3: P2 proline variants.",BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2004年 4月19日,Vol.14, No.8,P.1939-1942
PERNI, R.B. et al.,"Inhibitors of hepatitis C virus NS3・4A protease 2. Warhead SAR and optimization.",BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2004年 3月22日,Vol.14, No.6,P.1441-1446
YIN, Z. et al.,"Peptide inhibitors of dengue virus NS3 protease. Part 1: Warhead.",BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2006年 1月 1日,Vol.16, No.1,P.36-39
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita