Title:
貧血および赤血球機能不全を治療するためのＬＣＡＴの使用
Document Type and Number:
Japanese Patent JP5759988
Kind Code:
B2
Abstract:
Disclosed are methods for treating conditions characterized by anemia or red blood cells dysfunction by administering an agent that increases the level of endogenous LCAT or LCAT activity. Additionally disclosed are methods of treating conditions wherein red blood cells have reduced function in relation to deformability, oxygenation, increased adhesion and aggregability, reduced nitric oxide function, or decreased life-span, increased free cholesterol, or abnormal phospholipid content. Also disclosed are methods for treating conditions characterized by an abnormal concentration of free cholesterol in red blood cells and methods of normalizing the free cholesterol content of red blood cells.
Inventors:
Auerbach Bruce
Claus Brian
Hohmann Reynolds
Claus Brian
Hohmann Reynolds
Application Number:
JP2012515213A
Publication Date:
August 05, 2015
Filing Date:
June 14, 2010
Export Citation:
Assignee:
ALPHACORE PHARMA LLC
International Classes:
A61K38/45; A61P7/06
Foreign References:
| WO2009015314A1 | ||||
| WO2008108344A1 |
Other References:
SUDA T. et al,THE JOURNAL OF MEDICAL INVESTIGATION,2002年,Vol.49,p.147-155
Attorney, Agent or Firm:
Masahiro Nanjo
Takashi Matsuzaki
Takashi Matsuzaki