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Title:
ヒトの眼圧を低下させるための医薬組成物
Document Type and Number:
Japanese Patent JP5778663
Kind Code:
B2
Abstract:
Provided herein are compounds of Formula I, compositions comprising an effective amount of a compound of Formula I, and methods for reducing intraocular pressure comprising administering an effective amount of compounds of Formula I to a subject in need thereof.

Inventors:
Berman, Seeker
Baum Gartner, Rudolf A.
Application Number:
JP2012508764A
Publication Date:
September 16, 2015
Filing Date:
April 30, 2010
Export Citation:
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Assignee:
Innotek Pharmaceuticals Corporation
International Classes:
A61K31/52; A61K45/00; A61P27/02; A61P43/00
Domestic Patent References:
JP2008500361A
Other References:
AVILA,M.Y. et al,A1-, A2A- and A3-subtype adenosine receptors modulate intraocular pressure in the mouse,BRITISH JOURNAL OF PHARMACOLOGY,2001年,Vol. 134,pp.241-245
CROSSON,C.E. et al,Modulation of intraocular pressure by adenosine agonists,JOURNAL OF OCULAR PHARMACOLOGY,1994年,Vol.10, No. 1,pp.379-383
Current Eye Research,1992年,Vol.11,No.5,p.453-458
THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS,1995年,Vol.273,No.1,p.320-326
Exp. Eye. Res.,1997年,Vol.64,p.979-989
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Atsushi Honda