Title:
ヘキサヒドロインデノピリジン及びオクタヒドロベンゾキノリンのアリール−及びヘテロアリールカルボニル誘導体
Document Type and Number:
Japanese Patent JP5796015
Kind Code:
B2
Abstract:
wherein the variables R1, R2, R3, R4, and m are defined as in claim 1, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of 11β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity, and dyslipidemia.
Inventors:
Echult, Matthias
Peters, Stephan
Naru, Herbert
Himmelsbach, Frank
Tsang, Rinhan
Peters, Stephan
Naru, Herbert
Himmelsbach, Frank
Tsang, Rinhan
Application Number:
JP2012538024A
Publication Date:
October 21, 2015
Filing Date:
November 05, 2010
Export Citation:
Assignee:
Vity Pharmaceuticals, Inc.
Boehringer Ingelheim International GmbH
Boehringer Ingelheim International GmbH
International Classes:
C07D221/06; A61K31/473; A61K31/498; A61K31/501; A61K31/5377; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P43/00; C07D401/06; C07D401/14; C07D405/14; C07D417/06; C07D471/04; C07D498/04
Domestic Patent References:
| JP2006522748A | ||||
| JP2008515956A | ||||
| JP2006522746A |
Foreign References:
| WO2009063061A1 | ||||
| WO2009100872A1 |
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Keiko Ozawa
Toshio Miyake
Yasuhiro Oguni
Yoko Tanaka
Atsushi Shiomi
Fusayuki Saito
Hajime Tsukuni
Yasuo Yanagibashi
Keiko Ozawa
Toshio Miyake
Yasuhiro Oguni
Yoko Tanaka
Atsushi Shiomi
Fusayuki Saito
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