研究、判定又は評価法 - Nippon Organ Pharmaceutical Co., Ltd.

Title:

研究、判定又は評価法

Document Type and Number:

Japanese Patent JP5806694

Kind Code:

B2

Abstract:

A method for studying, determining or evaluating a pharmacological action of a test substance, the method including subjecting the brain tissue of an SART stressed animal administered with the test substance to an expression proteome analysis, where expression changes of NSF (N-ethylmaleimide sensitive fusion protein), which is or is not modified after translation, in the SART stressed animal administered with the test substance as compared with an SART stressed animal to which a test substance is not administered is used as an index.

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Inventors:

Hisuki Nishioka
Tomohiro Kato
Hiroki Fujisawa

Application Number:

JP2013048403A

Publication Date:

November 10, 2015

Filing Date:

March 11, 2013

Export Citation:

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Assignee:

Nippon Organ Pharmaceutical Co., Ltd.

International Classes:

G01N33/50; A61K35/36; A61K45/00; A61P21/00; A61P25/00; A61P25/04; A61P29/00; C12Q1/02; G01N33/15; G01N33/68

Foreign References:

WO2004039383A1

Other References:

呉晃一郎他,ワクシニアウイルス接種家兎炎症皮膚抽出物の鎮痛作用,基礎と臨床,1981年 5月,Vol.15, No.5,167-178ページ
石田友紀,プロテオミクスにおける蛋白質発現ディファレンシャル解析-蛍光標識二次元ディファレンス電気泳動,臨床検査,2003年,Vol.47 No.11,p.1269-1276

Attorney, Agent or Firm:

Ikuo Fujii

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