Title:
ＥＧＦファミリーリガンドのアンタゴニストを成分とする医薬組成物
Document Type and Number:
Japanese Patent JP5808052
Kind Code:
B2
Abstract:
The present inventors identified inhibition of a combination of EGFR ligands that serve as targets for inhibition of cancer cell proliferation. More specifically, EREG antagonists and TGF± antagonists were found to be useful as inhibitors of cell growth. The present invention relates to pharmaceutical compositions containing EGF family ligand antagonists as components.
Inventors:
Kenji Yoshida
Hirotaka Ito
Hirotaka Ito
Application Number:
JP2011516054A
Publication Date:
November 10, 2015
Filing Date:
May 27, 2010
Export Citation:
Assignee:
Chugai Pharmaceutical Co., Ltd.
International Classes:
A61K39/395; A61P35/00; A61P43/00; G01N33/15; G01N33/50
Foreign References:
| WO2008047723A1 | 2008-04-24 |
Other References:
JPN6014006411; Ｖｉｒｃｈｏｗｓ Ａｒｃｈｉｖ． Ｂ， Ｃｅｌｌ Ｐａｔｈｏｌｏｇｙ ｉｎｃｌｕｄｉｎｇ Ｍｏｌｅｃ Ｖｏｌ．５９，Ｎｏ．３, 1990, ｐ１７３-１７８
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto