Title:
新規ニトロレダクターゼ酵素基質
Document Type and Number:
Japanese Patent JP5823390
Kind Code:
B2
Abstract:
The invention relates to the use of a compound having formula (I) as an enzymatic substrate for the detection of a nitroreductase activity or as an enzymatic substrate for the detection of a nitroreductase activity and indicator of pH, wherein: W1, W2, W3 and W4 are independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination of same; n=0, 1 or 2; U and V are N, N+R, CZ4, R being H, alkyl, aralkyl, aryl, alkanoic or alkylsulphonic, preferably if U is CZ4, V is N or N+R and, if V is CZ4, U is N or N+R; and Z1, Z2, Z3 and Z4 are independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulphonyl, including the sulphonyl or carboxyl amides or esters thereof, and the salts of same.
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Inventors:
James, Arthur
Orenga, Sylvain
John Perry
Salwatura, Vindiya, Laxka
Stanforce, Stephen
Orenga, Sylvain
John Perry
Salwatura, Vindiya, Laxka
Stanforce, Stephen
Application Number:
JP2012522235A
Publication Date:
November 25, 2015
Filing Date:
July 29, 2010
Export Citation:
Assignee:
BIOMERIEUX
International Classes:
C12Q1/26; C12Q1/04
Other References:
Mutation Research,1986年,Vol.172,p.37-45
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori