Title:
単一ドメイン抗原結合分子の製剤
Document Type and Number:
Japanese Patent JP5823867
Kind Code:
B2
Abstract:
The invention relates to formulations of single domain antigen binding molecules, e.g. nanobody molecules, in particular formulations of TNF-binding nanobody molecules. The single domain antigen binding molecules can include one or more single binding domains that interact with, e.g. bind to, one or more target proteins. The formulations are useful, e.g., as pharmaceutical formulations. Method of preparing, and using the formulations described herein, to treat, e.g., TNF-associated disorders, are also disclosed.
Inventors:
Jason E. Fernandez
Daniel A. Dixon
Andrea Paulson
Daniel A. Dixon
Andrea Paulson
Application Number:
JP2011534779A
Publication Date:
November 25, 2015
Filing Date:
October 29, 2009
Export Citation:
Assignee:
Abrinks En.
International Classes:
A61K39/395; A61K9/08; A61K9/19; A61K47/14; A61K47/18; A61K47/26; A61P17/06; A61P19/02; A61P29/00; A61P37/00; G01N33/15
Domestic Patent References:
| JP2003516361A | ||||
| JP2006249083A | ||||
| JP2006249081A | ||||
| JP2006249084A | ||||
| JP11510170A |
Foreign References:
| WO2006122786A1 | ||||
| WO2007014073A1 |
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Toshio Miyake
Akio Shibata
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Hajime Tsukuni
Toshio Miyake
Akio Shibata
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa