Title:
脂肪肝疾患を処置するための方法
Document Type and Number:
Japanese Patent JP5836961
Kind Code:
B2
Abstract:
In certain aspects, the present invention provides compositions and methods for treating fatty liver disease by administering an antagonist of an ActRIIB signalling pathway. Examples of such antagonists include ActRIIB polypeptides, anti-ActRIIB antibodies, anti-myostatin antibodies, anti-GDF3 antibodies and anti-activin A or B antibodies. A variety of hepatic and metabolic disorders may be improved by treating fatty liver disease.
Inventors:
Konzerevich, Alan
Lucky, jennifer
Sarah, Jasbah
Sherman, Matthew El.
Lucky, jennifer
Sarah, Jasbah
Sherman, Matthew El.
Application Number:
JP2012537217A
Publication Date:
December 24, 2015
Filing Date:
November 03, 2010
Export Citation:
Assignee:
Axelron Pharma, Inc.
International Classes:
A61K38/00; A61K39/395; A61P1/16
Domestic Patent References:
| JP2008507288A | ||||
| JP2007099764A | ||||
| JP2009521452A | ||||
| JP2009528375A | ||||
| JP2009531280A | ||||
| JP2009519984A |
Foreign References:
| WO2008097541A1 |
Other References:
International Journal of Obesity,2009年11月 1日,Vol.33, No.11,p.1265-1273
World Journal of Gastroenterology,2006年,Vol.12, No.48,p.7826-7831
World Journal of Gastroenterology,2006年,Vol.12, No.48,p.7826-7831
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
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