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Title:
キャリアペプチドフラグメント及びその利用
Document Type and Number:
Japanese Patent JP5858283
Kind Code:
B2
Abstract:
The method for transferring a foreign substance provided by the present invention includes the steps of: preparing a construct for transferring a foreign substance that contains a carrier peptide fragment including either the amino acid sequence WRRQARFK (SEQ ID NO. 1) or any amino acid sequence formed by the substitution, deletion, and/or addition (insertion) of 1, 2, or 3 amino acid residues in the amino acid sequence, and a foreign substance of interest that is bonded to the N-terminus and/or C-terminus of the carrier peptide fragment; supplying the construct for transferring a foreign substance to a test sample that contains a target eukaryotic cell; and incubating the test sample that has been supplied with the construct for transferring a foreign substance to thereby transfer the construct into the eukaryotic cell in the test sample.

Inventors:
Naoko Kobayashi
Toru Yoshida
Niwa Mikio
Kenichi Tanaka
Application Number:
JP2011524808A
Publication Date:
February 10, 2016
Filing Date:
July 28, 2010
Export Citation:
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Assignee:
Toagosei Co., Ltd.
International Classes:
C12N15/09; A61K31/7052; A61K38/00; A61K45/00; A61K47/42; A61K47/48; A61K48/00; C07K7/06; C07K19/00
Domestic Patent References:
JP2001199997A2001-07-24
JP2004512275A2004-04-22
JP2001199997A2001-07-24
JP2004512275A2004-04-22
Attorney, Agent or Firm:
Makoto Abe
Michiko Oi