核酸コンジュゲートのためのエンドソーム溶解剤を用いた最適化ｉｎｖｉｖｏ送達システム

Japanese Patent JP5860874

B2

The present invention relates to an optimizedin vivodelivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.

JP4191796	A method of recovering a compound that is not known to be able to bind to the human ORL1 receptor as an antagonist or agonist.
JP2010248179	PHARMACEUTICAL COMPOSITION
JP2002541840	INDUSTRIAL APPLICABILITY A novel family of β subunit proteins derived from potential gated sodium channels, nucleic acids encoding them, and their therapeutic or diagnostic use.

Sun, Chen-Shen
Dutrex, Marie
Kwants, Maria

JP2013515845A

February 16, 2016

June 21, 2011

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DNA THERAPEUTICS
INSTITUT CURIE
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

A61K48/00; A61K31/4706; A61K45/00; A61K47/28; A61K47/48; A61P35/00; A61P35/02; A61P35/04; A61P43/00

JP2007510405A
JP2010515707A
JP2010504085A
JP5505941A
JP2000506504A
JP2002514892A
JP10500856A
JP10500309A

WO2009063998A1

Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Keiko Ozawa
Toshio Miyake
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Akio Shibata
Yuichi Okazaki

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