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Title:
クエン酸及び重炭酸塩を含んでなる医薬組成物、並びにシスチン尿症を治療するためのこれらの使用
Document Type and Number:
Japanese Patent JP5879359
Kind Code:
B2
Abstract:
A solid oral pharmaceutical composition in the form of tablets including:—a first solid oral pharmaceutical formulation in the form of at least one micro-tablet, the micro-tablet consisting of a core including at least one Krebs cycle precursor salt as active ingredient, and of a coating including at least one coating agent, and—a second oral pharmaceutical formulation in the form of at least one mini-tablet, the mini-tablet consisting of a core including at least one bicarbonate salt as active ingredient and at least one prolonged-release matrix, and of a coating including at least one coating agent. The use thereof as a medicament, in particular in the treatment and/or prevention of cystinuria.

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Inventors:
Catherine Guite
Backpack-Andre Granier
Calorie Nursel-Mopti
Application Number:
JP2013539318A
Publication Date:
March 08, 2016
Filing Date:
November 18, 2011
Export Citation:
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Assignee:
Adobesenne
International Classes:
A61K33/12; A61K9/28; A61K31/194; A61K31/7076; A61K47/12; A61K47/14; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/44; A61P13/04; A61P43/00
Domestic Patent References:
JP10087479A
JP6298641A
JP60197624A
JP11506778A
Foreign References:
WO1996039127A1
US3903255
US4451454
EP1970066A1
GB2130087A
Other References:
DAVID S GOLDFARB,URINARY ALKALIZATION,CYSTINURIA SUPPORT NETWORK [ONLINE],2008年 9月27日,P1-3,URL,http://www.cystinuria.com/articles/urinary-alkalization/
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei