Title:
キナーゼ誘発疾患の処置に有用なビピリジル誘導体
Document Type and Number:
Japanese Patent JP5886842
Kind Code:
B2
Abstract:
The present invention relates to novel bipyridyl derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.
Inventors:
Herzemann, Gunther
Dolsh Dieter
Youngzik, Alfred
Amento, Christiane
Zenke, frank
Dolsh Dieter
Youngzik, Alfred
Amento, Christiane
Zenke, frank
Application Number:
JP2013517056A
Publication Date:
March 16, 2016
Filing Date:
June 07, 2011
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D213/74; A61K31/444; A61K31/4545; A61K31/4709; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61K45/00; A61P9/10; A61P17/00; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P31/18; A61P35/00; A61P35/02; A61P35/04; A61P37/06; A61P43/00; C07D401/14; C07D471/04
Foreign References:
| WO2004014891A1 | ||||
| WO2009087212A1 | ||||
| WO2004013135A1 | ||||
| WO2009087224A1 |
Other References:
J. Med. Chem.,2006年,49,2210-2221
Attorney, Agent or Firm:
Kiyoji Kuzuwa
Noriki Mitsuhashi
Noriki Mitsuhashi
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