Title:
カイコを用いた糖鎖構造に特徴を有する糖蛋白質の製造方法
Document Type and Number:
Japanese Patent JP5893597
Kind Code:
B2
Abstract:
It is an object of the present invention to investigate what kinds of structures a sugar chain has by performing a sugar chain structural analysis of a glycoprotein produced in a transgenic silkworm. For the sugar chain of the glycoprotein produced in the transgenic silkworm, a glycoprotein having a sugar chain structure in which fucose is not linked to N-acetylglucosamine at a reducing terminal of the sugar chain is obtained. In addition, a glycoprotein having an almost completely humanized sugar chain structure is obtained by further integrating GalT gene into this transgenic silkworm.
Inventors:
Masahiro Tomita
Atsushi Hirabayashi
Shinichi Nakakita
Atsushi Hirabayashi
Shinichi Nakakita
Application Number:
JP2013211286A
Publication Date:
March 23, 2016
Filing Date:
October 08, 2013
Export Citation:
Assignee:
Immune Biology Research Institute, Inc.
NIPPON FLOUR MILLS CO.,LTD.
NIPPON FLOUR MILLS CO.,LTD.
International Classes:
A01K67/033; C12P21/02; C12N15/09; C12P21/08
Domestic Patent References:
| JP2007228814A | ||||
| JP2006137739A | ||||
| JP2006109772A | ||||
| JP2003325188A |
Foreign References:
| WO2007046439A1 |
Other References:
第31回日本分子生物学会年会・第81回日本生化学会合同大会 講演要旨集, 2008.11.20, p. 511(2P-1455)
繊維研究所研究報告, 2003.03.30, no. 6, p. 1-8
第27回 日本分子生物学会年会 プログラム・講演要旨集,2004年,p.1016 (3PB-534)
繊維研究所研究報告, 2003.03.30, no. 6, p. 1-8
第27回 日本分子生物学会年会 プログラム・講演要旨集,2004年,p.1016 (3PB-534)
Attorney, Agent or Firm:
sk patent corporation
Akihiko Okuno
Hiroyuki Ito
Akihiko Okuno
Hiroyuki Ito
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