Title:
ヒトＧＤＦ８に対する抗体
Document Type and Number:
Japanese Patent JP5896993
Kind Code:
B2
Abstract:
The present invention provides isolated human or humanized antibodies or antigen-binding fragments thereof which specifically bind to Growth and Differentiation Factor-8 (GDF8) and block GDF8 activity. The antibodies and antibody fragments of the present invention may be used in therapeutic methods for treating conditions or disorders which are ameliorated or improved by inhibition of GDF8.
Inventors:
Trevor Stitt
Esther Rattress
Esther Rattress
Application Number:
JP2013512186A
Publication Date:
March 30, 2016
Filing Date:
May 25, 2011
Export Citation:
Assignee:
REGENERON PHARMACEUTICALS, INC.
International Classes:
C07K16/24; A61K39/395; A61P7/00; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P21/04; C12N15/02; C12N15/09
Domestic Patent References:
| JP2009511480A | ||||
| JP2007530551A | ||||
| JP2010502633A | ||||
| JP2008539241A |
Foreign References:
| WO2009058346A1 |
Other References:
Cancer Res,2009年,Vol.69,Abstract No. 4650
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi