Title:
酵素ＰＤＥ１０Ａ阻害剤としてのヘテロ芳香族フェニルイミダゾール誘導体
Document Type and Number:
Japanese Patent JP5901535
Kind Code:
B2
Abstract:
This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
Inventors:
Pushur, Ask
Nielsen, Jacob
Kefler, Yang
Kilburn, John, Paul
Marigot, Mauro
Langard, Molten
Nielsen, Jacob
Kefler, Yang
Kilburn, John, Paul
Marigot, Mauro
Langard, Molten
Application Number:
JP2012543475A
Publication Date:
April 13, 2016
Filing Date:
December 15, 2010
Export Citation:
Assignee:
Her Lundbeck Actiezer Scabet
International Classes:
C07D471/04; A61K31/437; A61K31/4985; A61K31/519; A61P25/14; A61P25/16; A61P25/28; A61P25/30; A61P25/32; C07D487/04
Domestic Patent References:
| JP2011524381A | ||||
| JP2009522346A | ||||
| JP2013514285A |
Foreign References:
| WO2008004117A1 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Taro Ushio
Yasuhito Suzuki
Norio Omori
Taro Ushio
Yasuhito Suzuki