Title:
非分節型マイナス鎖ＲＮＡウイルスを作出するための細胞及び方法
Document Type and Number:
Japanese Patent JP5902371
Kind Code:
B2
Abstract:
The present invention relates to recombinant cells as well as to methods for the generation of non-segmented negative-sense single-stranded RNA viruses (NNV or mononegavirales) from cloned deoxyribonucleic acid (cDNA), especially from measles virus and in particular from attenuated strains such as those approved for vaccination, in particular from the attenuated Schwarz measles virus and various recombinant Schwarz measles-based viruses expressing heterologous sequences. Such rescued viruses can be used, after amplification, as vaccines for immunization against measles and/or against the heterologous peptides or proteins expressed.
Inventors:
Tansy, frederick
Charnot, Pierre
Jacob, Eve
Charnot, Pierre
Jacob, Eve
Application Number:
JP2009542273A
Publication Date:
April 13, 2016
Filing Date:
December 21, 2007
Export Citation:
Assignee:
INSTITUT PASTEUR
International Classes:
C12N15/09; C12N5/10; C12N7/00; C12N7/01; C12N7/04
Domestic Patent References:
| JP2003511083A | ||||
| JP2004503233A |
Foreign References:
| WO1997006270A1 | ||||
| WO2005111221A1 | ||||
| WO2005056781A1 | ||||
| WO2006108241A1 |
Other References:
EMBO J.,1995,Vol.14,No.23,p.5773-5784
J.Virol.,2003年,Vol.77,No.21,p.11546-11554
Mol.Ther.,2001年,Vol.3,No.4,p.438-448
Nat.Biotechnol.,2001年,Vol.19,No.5,p.446-450
Gene Ther.,2005年,Vol.12,No.23,p.1667-1678
実験医学,1994年,Vol.12,No.15,p.47-51
ウイルス,2002年,Vol.52,No.2,p.225-231
J.Virol.,2003年,Vol.77,No.21,p.11546-11554
Mol.Ther.,2001年,Vol.3,No.4,p.438-448
Nat.Biotechnol.,2001年,Vol.19,No.5,p.446-450
Gene Ther.,2005年,Vol.12,No.23,p.1667-1678
実験医学,1994年,Vol.12,No.15,p.47-51
ウイルス,2002年,Vol.52,No.2,p.225-231
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima