Title:
関連アプリケーションに相互参照する有効関連値を使用する対立遺伝子識別解析
Document Type and Number:
Japanese Patent JP5922204
Kind Code:
B2
Abstract:
In various embodiments this invention provides novel methods for discriminating two or more different target nucleic acids. In certain embodiments the methods comprise providing data amplification reactions comprising reagents to amplify two or more different target nucleic acids where the data comprise signals comprising an amplitude measurement representing the degree of amplification of each target nucleic acid in the amplification reaction and the time point in the amplification reaction at which the amplitude is measured; determining an efficiency related transform of the data, determining an efficiency related value for each target nucleic acid that is the maximum magnitude of the efficiency related transform; and outputting the efficiency related values in the amplification reaction for each target nucleic acid, where the relative amplitudes of the efficiency related values for each target nucleic acid is an indicator of the presence of each of said nucleic acids in said sample.
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Inventors:
Eric Bee Shine
Application Number:
JP2014178854A
Publication Date:
May 24, 2016
Filing Date:
September 03, 2014
Export Citation:
Assignee:
Abbott Morequiller Incorporated
International Classes:
C12N15/09; G16B40/10; C12M1/00; C12Q1/68
Domestic Patent References:
| JP2007521802A |
Foreign References:
| WO2007056463A2 |
Other References:
J. Virol. Methods,2007年 5月,vol.141, no.2,pp.205-211
BioTechniques,2007年10月,vol.43, no.4,pp.517-519
BioTechniques,2007年10月,vol.43, no.4,pp.517-519
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro