新規の蛍光性ホウ素で置換されたジピロメテン及び診断へのその使用

Title:

新規の蛍光性ホウ素で置換されたジピロメテン及び診断へのその使用

Document Type and Number:

Japanese Patent JP5924939

Kind Code:

B2

Abstract:

The invention relates to novel fluorescent compounds derived from non-fluorinated dipyrromethene-boron, to a method for preparing same and to the use thereof for the fluorescent marking of biological molecules. The invention also relates to biological molecules marked with said fluorescent compounds, and to the use thereof in detection methods such as medical diagnosis methods. More particularly, the detection methods of the invention are particularly useful for diagnosing neurodegenerative diseases such as Alzheimer's disease.

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Inventors:

De barry jean
Rijois Corinne
Aefel Alexandre
Buratoma
Ulrich Jill
Theel Raymon

Application Number:

JP2011542864A

Publication Date:

May 25, 2016

Filing Date:

December 28, 2009

Export Citation:

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Assignee:

ECOLE NORMALE SUPERIEURE
UNIVERSITE DE STRASBOURG

International Classes:

C07F5/02; C07K14/47; C12N5/00; G01N21/78; G01N33/53; G01N33/533; G01N33/58

Domestic Patent References:

JP2012513974A
JP2008530063A

Other References:

Chemistry - A European Journal,2009年,15(26),6335-6339

Attorney, Agent or Firm:

Patent Business Corporation Saegusa International Patent Office

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