Title:
偏極移行を使用する高静磁場（Ｂ０）における広帯域幅磁気共鳴分光法
Document Type and Number:
Japanese Patent JP5932844
Kind Code:
B2
Abstract:
A magnetic resonance (MR) generating a static (BO) magnetic field of 5 Tesla or higher controller is configured to control an MR scanner to perform an MR sequence (14) including: performing an excitation/localization sub-sequence (30) on a subject disposed in the static (BO) magnetic field generated by the MR scanner to excite 1H polarization in a selected spatial region of the subject; performing 5 a polarization transfer sub-sequence (32) to transfer localized 1H polarization generated by the excitation/localization sub-sequence to a selected species of non-proton nuclei; and performing a magnetic resonance spectroscopy (MRS) readout sub-sequence (40) to acquire MRS data for the selected species of non-proton nuclei in the selected spatial region of the subject. The polarization transfer sub-sequence includes a pair of phase 10 distortion canceling trapezoidal 180° refocusing pulses (36, 37) operating on the selected species of non-proton nuclei.
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Inventors:
Yamba Orien
Foxall David Leslie
Foxall David Leslie
Application Number:
JP2013553051A
Publication Date:
June 08, 2016
Filing Date:
January 10, 2012
Export Citation:
Assignee:
KONINKLIJKE PHILIPS N.V.
International Classes:
A61B5/05; A61B5/055; G01R33/28
Other References:
Su Xu, Jun Shen,“In vivo dynamic turnover of cerebral 13C isotopomers from [U-13C]glucose”,Journal of Magnetic Resonance,2006年10月,Vol.182 Issue.2,P221-P228
Shizhe Li, et al.,“In vivo single-shot, proton-localized 13C MRS of rhesus monkey brainy”,NMR IN BIOMEDICINE,2005年11月 4日,Vol.18,P560-P569
D.W.J.Klomp, et al.,“Polarization transfer for sensitivity-enhanced MRS using a single radio frequency transmit channel”,NMR IN BIOMEDICINE,2007年10月 4日,Vol.21,P444-452
Eriks Kupce, Ray Freeman,“Compensated adiabatic inversion pulses: Broadband INEPT and HSQC”,Journal of Magnetic Resonance,2007年 5月17日,Vol.187,P258-P265
Jun Shen, et al.,Implementation of Adiabatic Polarization Transfer for Localized 13C NMR Spectroscopy on a Whole-body Spectrometer,Proceedings of International Society for Magnetic Resonance in Medicine[CD-ROM],1997年 4月12日
Shizhe Li, et al.,“In vivo single-shot, proton-localized 13C MRS of rhesus monkey brainy”,NMR IN BIOMEDICINE,2005年11月 4日,Vol.18,P560-P569
D.W.J.Klomp, et al.,“Polarization transfer for sensitivity-enhanced MRS using a single radio frequency transmit channel”,NMR IN BIOMEDICINE,2007年10月 4日,Vol.21,P444-452
Eriks Kupce, Ray Freeman,“Compensated adiabatic inversion pulses: Broadband INEPT and HSQC”,Journal of Magnetic Resonance,2007年 5月17日,Vol.187,P258-P265
Jun Shen, et al.,Implementation of Adiabatic Polarization Transfer for Localized 13C NMR Spectroscopy on a Whole-body Spectrometer,Proceedings of International Society for Magnetic Resonance in Medicine[CD-ROM],1997年 4月12日
Attorney, Agent or Firm:
Susumu Tsugaru
Fueda Shusen
Fueda Shusen