Title:
サイトメガロウイルスの阻害剤
Document Type and Number:
Japanese Patent JP6372666
Kind Code:
B2
Abstract:
Compounds of Formula (I) wherein n, R1, R1A, R2, R4 and Z are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
Inventors:
Fadel lee
Parisian Matthew
Tibor curl
Molency Lewis
Dupless Martin
James Clint
Morin Sebastian
Gillard james
Parisian Matthew
Tibor curl
Molency Lewis
Dupless Martin
James Clint
Morin Sebastian
Gillard james
Application Number:
JP2015540765A
Publication Date:
August 15, 2018
Filing Date:
October 31, 2013
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D277/56; A61K31/426; A61K31/427; A61K31/428; A61K31/4439; A61K31/497; A61K31/5377; A61P31/22; C07D277/82; C07D417/12; C07D417/14
Domestic Patent References:
| JP2010502663A | ||||
| JP2002531554A |
Foreign References:
| WO2010142752A1 | ||||
| WO2009011850A1 |
Other References:
ENGERS, D. W. ET AL,Discovery, Synthesis, and Structure-Activity Relationship Development of a Series of N-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in Rats,Journal of Medicinal Chemistry,2011年,54(4),1106-1110
RN 1244943-22-3 REGISTRY,DATABASE REGISTRY [ONLINE] Retrieved from STN,2010年10月 3日,検索日: 20 SEP 2017,N-[3-(ベンゾイルアミノ)-4-メトキシフェニル]-1,2,3-チアジアゾール-4-カルボキサミド
BLOOM, J. D. ET AL,Thiourea inhibitors of herpes viruses. Part 1: Bis-(aryl)thiourea inhibitors of CMV,Bioorganic & Medicinal Chemistry Letters,2003年,13(17),2929-2932
C.G.WERMUTH編,『最新 創薬化学 上巻』,株式会社テクノミック,1998年 8月15日,235-271頁,13章 等価置換に基づく分子の変換
野崎正勝ら,創薬化学,化学同人,1995年 7月 1日,p.98-99
RN 1244943-22-3 REGISTRY,DATABASE REGISTRY [ONLINE] Retrieved from STN,2010年10月 3日,検索日: 20 SEP 2017,N-[3-(ベンゾイルアミノ)-4-メトキシフェニル]-1,2,3-チアジアゾール-4-カルボキサミド
BLOOM, J. D. ET AL,Thiourea inhibitors of herpes viruses. Part 1: Bis-(aryl)thiourea inhibitors of CMV,Bioorganic & Medicinal Chemistry Letters,2003年,13(17),2929-2932
C.G.WERMUTH編,『最新 創薬化学 上巻』,株式会社テクノミック,1998年 8月15日,235-271頁,13章 等価置換に基づく分子の変換
野崎正勝ら,創薬化学,化学同人,1995年 7月 1日,p.98-99
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Maki Kubota
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Maki Kubota