ゲル組成物 - Laboratorios Oher Pharma Ese. Ele.

Title:

ゲル組成物

Document Type and Number:

Japanese Patent JP6382215

Kind Code:

B2

Abstract:

The present invention provides a gel combination comprising: polycarbophil in an amount comprised from 1 to 5% by weight; polyvinylpirrolidone in an amount comprised from 4 to 8% by weight; glycerine in an amount comprised from 1 to 10% by weight; and propyleneglycol in an amount comprised from 20 to 40% by weight; wherein: the weight ratio between polyvinylpirrolidone:polycarbophil is comprised between 1:1 and 4:1, the weight ratio between glycerine:polycarbophil is comprised from 0.5:1 to 2:1, and the weight ratio propyleneglycol:polycarbophil is comprised from 8:1 to 20:1. The invention also provides transparent compositions comprising such gel combinations as well as processes for their preparation and the use thereof as a medicament. Due to the specific excipients, % by weight, and weight ratios forming the combination, the resulting compositions show a high bioadhesivity and bioavailablity of the active ingredient, without toxic adverse effects.

Inventors:

Gonzales Ohel, Carlos
Da Costa Martin, Laquer Maria
Sne Negre, Giusep Emme.
Minyaro Carmona, Montserrat
Tiko Grau, Josep Ramon
Garcia Montja, Encarna
Perez Rosano, Pilar
Roy Carreras, Manel
Sanchez Porqueras, Natalia

Application Number:

JP2015547061A

Publication Date:

August 29, 2018

Filing Date:

December 16, 2013

Export Citation:

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Assignee:

Laboratorios Oher Pharma Ese. Ele.

International Classes:

A61K47/32; A61K9/06; A61K47/10; A61K47/18

Domestic Patent References:

JP2011121983A
JP7223938A
JP2002507561A

Foreign References:

EP1413292A1
WO2005074883A1

Attorney, Agent or Firm:

Sonoda/Kobayashi Patent Business Corporation

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