Title:
ヒトＴｏｌｌ様受容体阻害剤およびその使用方法
Document Type and Number:
Japanese Patent JP6395266
Kind Code:
B2
Abstract:
Provided herein are human Toll-like receptor (TLR)-inhibitors and methods for use in individuals having an autoimmune disease or an inflammatory disorder. The TLR inhibitors of the present disclosure are polynucleotides comprising an inhibitory motif for one or more of TLR7, TLR8 and TLR9.
Inventors:
Guiducci, Christiana
Farron, Karen El.
Barratt, frank
Farron, Karen El.
Barratt, frank
Application Number:
JP2015534781A
Publication Date:
September 26, 2018
Filing Date:
September 27, 2013
Export Citation:
Assignee:
Dynabux Technologies Corporation
International Classes:
C12N15/117; A61K31/7115; A61K31/7125; A61P29/00; A61P37/06
Foreign References:
| WO2011159958A1 | ||||
| WO2009055076A1 | ||||
| WO2006066003A1 | ||||
| US20070238678 | ||||
| WO2007117686A1 |
Other References:
LU X. et al,Arch Virol,151(2006),p.1587-1602
KAJON A.E. et al,Methods in Molecular Medicine,Vol.131(2007),p.335-355
HUI YU,CURRENT MEDICINAL CHEMISTRY,2012年 3月 1日,V19 N9(2012.3),P1365-1377
KAJON A.E. et al,Methods in Molecular Medicine,Vol.131(2007),p.335-355
HUI YU,CURRENT MEDICINAL CHEMISTRY,2012年 3月 1日,V19 N9(2012.3),P1365-1377
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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