Title:
ＦＴ−ＩＣＲ−ＭＳ／ＭＳを使用した、歯肉炎および歯周炎のバイオマーカーのための唾液プロテオームの分析
Document Type and Number:
Japanese Patent JP6402106
Kind Code:
B2
Abstract:
Methods for diagnosing the status of periodontitis disease includes selecting a set of protein biomarkers including one or more biomarkers which have been shown to vary in abundance at particular stages of periodontitis. The set of protein biomarkers may be identified and quantified in expression in an acquired gingival crevicular fluid (GCF) or saliva oral fluid sample in order to distinguish between different states of periodontitis. Methods of diagnosing the status of periodontitis oral disease at varying levels of severity, e.g. gingivitis, mild periodontitis, or severe periodontitis, may include selecting a set of protein biomarkers which are capable distinguishing between different stages of periodontitis.
Inventors:
Chaplin, Ian
Creese, Andrew
Grant, Melissa
Creese, Andrew
Grant, Melissa
Application Number:
JP2015530542A
Publication Date:
October 10, 2018
Filing Date:
September 10, 2013
Export Citation:
Assignee:
KONINKLIJKE PHILIPS N.V.
International Classes:
G01N33/68
Domestic Patent References:
| JP10511469A | ||||
| JP2011521215A | ||||
| JP2005201768A | ||||
| JP2009145220A |
Foreign References:
| WO2009138392A1 | ||||
| US20100196941 | ||||
| WO1995012124A1 |
Attorney, Agent or Firm:
Tadashige Ito
Tadahiko Ito
Shinsuke Onuki
Tadahiko Ito
Shinsuke Onuki