Title:
ペプチド
Document Type and Number:
Japanese Patent JP6407888
Kind Code:
B2
Abstract:
There is provided a peptide which is capable of binding to an MHC molecule in vitro and being presented to a T cell without antigen processing (i.e. an apitope) which peptide comprises all or a portion of the following proteolipid protein (PLP) peptides: PLP 36-61: HE ALTGTEKLIET YF SKN YQD YEYLI (SEQ ID NO. 1) PLP 179-206: TWTTCQSIAFPSKTSASIGSLCA-DARMY (SEQ ID NO. 2) PLP 207-234: GVLPWNAFPGKVCGSNLLSICKTAEFQM (SEQ ID NO. 3). There is also provided the use of such a peptide in a pharmaceutical composition and a method to treat and/or prevent a disease using such a peptide.
Inventors:
Wraith, David
Heather, heather
Ordones, Lawrence
Heather, heather
Ordones, Lawrence
Application Number:
JP2015552189A
Publication Date:
October 17, 2018
Filing Date:
January 13, 2014
Export Citation:
Assignee:
Apitope Technology (Bristol) Limited
International Classes:
C07K14/47; A61K38/10; A61P25/00; C07K7/08
Foreign References:
| US20050037422 | ||||
| WO1997035879A1 |
Attorney, Agent or Firm:
Hiraki International Patent Office