Title:
鼻および眼へのコルチコステロイド水溶液送達
Document Type and Number:
Japanese Patent JP6409090
Kind Code:
B2
Abstract:
An inhalable formulation containing SAE-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueous solution, however, it can be stored as a dry powder, ready-to-use solution, or concentrated composition. The formulation is employed in an improved nebulization system for administering corticosteroid by inhalation. SAE-CD present in the formulation significantly enhances the chemical stability of budesonide. A method of administering the formulation by inhalation is provided. The formulation can also be administered by conventional nasal delivery apparatus.
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Inventors:
Pipkin, James Dee
Zimmerer, Rupert Oh
Seabert, John M
Zimmerer, Rupert Oh
Seabert, John M
Application Number:
JP2017088045A
Publication Date:
October 17, 2018
Filing Date:
April 27, 2017
Export Citation:
Assignee:
Sidex Pharmaceuticals, Inc.
International Classes:
A61K9/08; A61K31/55; A61K9/12; A61K31/335; A61K31/4174; A61K31/4545; A61K31/495; A61K31/506; A61K31/58; A61K31/7052; A61K39/395; A61K45/00; A61K47/10; A61K47/32; A61P37/08; A61P43/00
Domestic Patent References:
| JP6140321B2 | ||||
| JP11511758A | ||||
| JP2004529167A | ||||
| JP2006517981A |
Foreign References:
| WO2006058022A1 | ||||
| WO2005065435A1 |
Other References:
ACTA OPHTHALMOLOGICA SCANDINAVICA,2002年,Vol.80,p.144-150
Attorney, Agent or Firm:
Shinjiro Ono
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Akiko Nakahama
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Akiko Nakahama