Title:
肺高血圧症治療剤
Document Type and Number:
Japanese Patent JP6419085
Kind Code:
B2
Abstract:
[Solution] A positive allosteric regulator of a PGI2 receptor which comprises a compound represented by formula (1) or a pharmaceutically acceptable salt, hydrate or solvate thereof. (1) (In the formula, R1 is a branched chain or cyclic alkyl or alkenyl having 3 to 10 carbon atoms which may be substituted, R2 is a hydrogen atom or an alkyl having 1 to 6 carbon atoms which may be substituted, R3 is 1 to 4 substituents which are the same or different independently selected from the group consisting of a hydrogen atom, a halogen atom, an alkyl having 1 to 6 carbon atoms which may be substituted, and an alkoxy having 1 to 6 carbon atoms which may be substituted, and A is an aryl which may be substituted or a heteroaryl which may be substituted.)
Inventors:
Tetsuo Nagano
Takayoshi Okabe
Hiroshi Kojima
Satoshi Suzuki
Kenjiro Hanaoka
Shimonishi Manabu
Shinichiro Egashira
Hiroshi Nakano
Kazuo Kumagai
Hiroyuki Miyaji
Kenji Matsuno
Minoru Waki
Takayoshi Okabe
Hiroshi Kojima
Satoshi Suzuki
Kenjiro Hanaoka
Shimonishi Manabu
Shinichiro Egashira
Hiroshi Nakano
Kazuo Kumagai
Hiroyuki Miyaji
Kenji Matsuno
Minoru Waki
Application Number:
JP2015550974A
Publication Date:
November 07, 2018
Filing Date:
November 27, 2014
Export Citation:
Assignee:
National University Corporation Tokyo University
International Classes:
A61K31/4725; A61K31/416; A61K31/4174; A61K31/4365; A61K31/5578; A61K31/5585; A61K45/00; A61P9/12; A61P11/00; A61P43/00; C07D401/06; C07D495/04
Foreign References:
| US20100210836 |
Attorney, Agent or Firm:
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Yoshikazu Iwase
Yasufumi Shiroyama
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Yoshikazu Iwase
Yasufumi Shiroyama
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