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Title:
ミクロソームプロスタグランジンE2シンターゼ-1を阻害するのに有用な新規カルボン酸化合物
Document Type and Number:
Japanese Patent JP6425809
Kind Code:
B2
Abstract:
The present invention provides compounds of Formula 1, or a pharmaceutically acceptable salts, thereof, where R, X, A, E, and G are as described herein, methods of preparing the compounds, and use of the compounds to treat pain and/or inflammation.

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Inventors:
Matthew Joseph Fisher
Stephen Lee Kukurish
Catherine Marie Partridge
Jeremy Schulenberg York
Application Number:
JP2017522854A
Publication Date:
November 21, 2018
Filing Date:
October 22, 2015
Export Citation:
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Assignee:
Eli Lilly and Company
International Classes:
C07C235/40; A61K31/196; A61K31/451; A61K31/4545; A61K31/4709; A61P25/04; A61P29/00; A61P43/00; C07D211/62; C07D401/04; C07D401/12
Domestic Patent References:
JP2008524325A
Other References:
KABLAOUI, N. et al.,Novel benzoxazole inhibitors of mPGES-1,Bioorganic & Medicinal Chemistry Letters,2013年,Vol.23,p.907-911
Attorney, Agent or Firm:
Samejima Mutsumi
Yasushi Morimoto
Nobuhiko Akiyama



 
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