Title:
抗ホスホリパーゼD4抗体を含む医薬
Document Type and Number:
Japanese Patent JP6431523
Kind Code:
B2
Abstract:
The present application provides the medicaments comprising the antibodies binding to phospholipase D4 (PLD4) as well as a method using said medicaments for detecting and suppressing activated B cells. The present application is further directed to therapy of auto-immune diseases and allergosis, resulting from the active-repressing function. In order to solves these problems, the present application provides that a monoclonal antibody binding to the extracellular domain of phospholipase D4 (PLD4) protein, or a fragment containing an antigen-binding region thereof as an active ingredient.
Inventors:
Tomohide Yamazaki
Mayu Endo
Koji Ishida
Mayu Endo
Koji Ishida
Application Number:
JP2016503264A
Publication Date:
November 28, 2018
Filing Date:
July 30, 2014
Export Citation:
Assignee:
SBI Biotech Co., Ltd.
International Classes:
A61K39/395; A61P37/06; A61P37/08; C12Q1/04; G01N33/53; G01N33/577
Foreign References:
| WO2013115410A2 |
Other References:
PLoS ONE,2011年11月,6(11),e27544
PLoS ONE,2010年11月,5(11),e13932
Nature Genetics,2012年 5月,44(5),p.511-516
Arthritis & Rheumatism,2013年 2月,65(2),p.472-480
PLoS ONE,2010年11月,5(11),e13932
Nature Genetics,2012年 5月,44(5),p.511-516
Arthritis & Rheumatism,2013年 2月,65(2),p.472-480
Attorney, Agent or Firm:
Asamura patent office