Title:
１，２，４−トリアゾロ［４，３−ａ］ピリジン化合物およびＭＧＬＵＲ２受容体の正のアロステリック調節因子としてのそれらの使用
Document Type and Number:
Japanese Patent JP6449297
Kind Code:
B2
Abstract:
The present invention relates to novel 1,2,4-triazolo[4,3-a]pyridine compounds as positive allosteric modulators (PAMs) of the metabotropic glutamate receptor subtype 2 (“mGluR2”). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which mGluR2 subtype of metabotropic receptors is involved.
Inventors:
Sid-Nynes, Jose, Maria
Travanco-Suare, Andre, Avellino
Lovelysen, Hilde
The Stars, Marc Andre
Travanco-Suare, Andre, Avellino
Lovelysen, Hilde
The Stars, Marc Andre
Application Number:
JP2016539518A
Publication Date:
January 09, 2019
Filing Date:
September 03, 2014
Export Citation:
Assignee:
Janssen Pharmaceuticals N.B.
International Classes:
C07D471/04; A61K31/437; A61P9/10; A61P25/00; A61P25/06; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/34; A61P43/00
Domestic Patent References:
| JP2008543764A | ||||
| JP2010527974A | ||||
| JP2012526737A |
Foreign References:
| WO2012062750A1 | ||||
| WO2012062759A1 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Junko Kobayashi
Uetake Yukiko
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Junko Kobayashi
Uetake Yukiko
Yasuhito Suzuki
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